rexresearch.com

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UPDATED 20 FEBRUARY

https://news.yahoo.com/fountain-youth-study-finds-anti-ageing-compound-plant-160025864.html

 In Japan, the slightly bitter leaves of the Ashitaba plant have long been considered healthy, and a new study has found the traditional belief may have good scientific grounds.

A natural substance in the plant appears to induce a key process that helps remove the "cellular garbage" that can build up as cells age and cause a range of diseases and disorders.

"It is always nice to find a scientific rationale for traditional medical folk tales," said Frank Madeo, a professor at the University of Graz's Institute of Molecular Biosciences, in Austria.

Madeo, who helped lead the research, said the substance known as 4,4'-dimethoxychalcone or DMC, which occurs naturally in Ashitaba plants, induces a process called autophagy.

"This is a cleansing and recycling process," he told AFP. It removes "superfluous material, especially cellular garbage like aggregated proteins."

That "cleaning" process is key to sustained good health as the body ages. When cells fail to promptly and efficiently remove damaged parts, they can build up and that can lead to diseases including cancer.

There are already a handful of compounds known to scientists that work to stimulate the cleaning process. Fasting also appears to naturally encourage cells to undertake spring cleaning.

But in a bid to expand the field of compounds able to protect cells and turn back the hands of time, the team of researchers turned to a class of substances called flavonoids.

Many flavonoids have already been shown to have a range of beneficial effects, ranging from anti-inflammatory properties to protecting against brain degeneration and cancer.

The team reasoned that they might find flavonoids that could also help prevent destructive ageing in cells.

They screened 180 compounds representing various subcategories of flavonoids, looking for candidates that might have the natural ability to "counteract age-related cell demise."

Cell-protective capacity -

After initial screening, they settled on DMC and started by testing how the substance affected yeast cells.

They discovered it was indeed helping to protect the yeast cells from the effects of ageing, and that the substance performed as well or even better than some existing compounds prized for their cell-protective capacity like resveratrol, which occurs in grape skin, among other places.

The team then tested DMC's effect on cells in both worms and fruit flies -- common test subjects in medical research.

"Remarkably, chronic DMC treatment... prolonged the median lifespan of both model organisms by approximately 20 percent," the study published Wednesday in the Nature Communications journal says.

Additional tests showed the compound helped protect cells in mice hearts through the autophagy process, and even protected against a kind of liver damage caused by ethanol intoxication.

The team also tested DMC's effect on several types of human cells and found that there too the substance worked to slow ageing.

"The experiments indicate that the effects of DMC might be transferable to humans, although we have to be cautious and wait for real clinical trials," said Madeo.

The research is still in the early stages and Madeo said next steps will include testing whether the positive effects of DMC in mice hearts extend more broadly to protect mice against ageing and age-related diseases.

"Eventually, clinical trials on humans are needed," he added.

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https://www.youtube.com/watch?v=vaDrbTbkHms

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http://82.221.129.208/.xp6.html

In This five minute video the plight of a CNN reporter who blew the whistle on CNN's fraud for governments is gone over thoroughly and then video of her actually talking about it is shown. She states that CNN accepts payouts from corrupt governments that has them publish what they want, in exchange for huge payouts to CNN. Facts don't matter, it is whatever whoever pays CNN to say that gets presented and published. They are a for-pay propaganda outlet, this video busts them totally.

https://www.youtube.com/watch?v=wO4hP3y0Ovo

"Infomercials for dictators"

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https://www.youtube.com/watch?v=8ESuy3snZes

Video footage from a ranch in Arizona shows thousands of illegal aliens marching into the United States uninterrupted because there is no border wall, nor border patrol, to stop them.

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https://www.rt.com/viral/370554-mice-aging-process-reversed/

https://www.cell.com/cell/fulltext/S0092-8674(16)31664-6

Highlights
Partial reprogramming erases cellular markers of aging in mouse and human cells
Induction of OSKM in progeria mice ameliorates signs of aging and extends lifespan
In vivo reprogramming improves regeneration in 12-month-old wild-type mice

Summary
Aging is the major risk factor for many human diseases. In vitro studies have demonstrated that cellular reprogramming to pluripotency reverses cellular age, but alteration of the aging process through reprogramming has not been directly demonstrated in vivo. Here, we report that partial reprogramming by short-term cyclic expression of Oct4, Sox2, Klf4, and c-Myc (OSKM) ameliorates cellular and physiological hallmarks of aging and prolongs lifespan in a mouse model of premature aging. Similarly, expression of OSKM in vivo improves recovery from metabolic disease and muscle injury in older wild-type mice. The amelioration of age-associated phenotypes by epigenetic remodeling during cellular reprogramming highlights the role of epigenetic dysregulation as a driver of mammalian aging. Establishing in vivo platforms to modulate age-associated epigenetic marks may provide further insights into the biology of aging.

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https://www.realclearscience.com/blog/2019/02/14/the_miles_per_gallon_illusion.html?utm_medium=referral&utm_source=mixi&utm_campaign=realclearpolitics

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http://gratisenergi.se/hfet.htm

...a more effective version of Figuera generator patent. I my version the input coil is in the middle and is energising the output coils to left and right. While the Figuera patent the input coils are at the end and is energising the central coil, but half of the magnetic energy are lost to air, because the outer ends of the generator coils faces air...

Prophecy @ YouTube
This is as fanatical as it gets for Xtianity:

https://www.youtube.com/watch?v=C8o9Sx-f_Y4

https://www.youtube.com/watch?v=JgWYnDLTLEw

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Israel Mega-Sux :

https://www.veteranstoday.com/2019/02/19/anti-semitic-how-the-rule-of-the-rabbis-is-fueling-a-holy-war-in-israel/

Islam: The sadistic "Religion" of Barbarians --

https://www.youtube.com/watch?v=t_Qpy0mXg8Y

https://www.youtube.com/watch?v=z8ASaZvVqb8
[ Spoiler Alert : Ignore John of God @ 1:04 ]

https://www.youtube.com/watch?v=s95tF4n9MkE

https://www.youtube.com/watch?v=ibG1P6cOEOc&list=PL7726A6270E80743A

https://www.youtube.com/watch?v=uaWbJDGrVQM

https://www.youtube.com/watch?v=tTyn4WgZu3U

https://www.youtube.com/watch?v=vLA0MJA97vs

Nikolaas van Rensburg predicted the first, second and Third World War. According to his views the White South Afrikaner boers would get help from Imperial Germans during the last war of liberation at the End of Times. The Imperial Germans would give the boers weapons to be able to defend themselves against the indians and blacks that have been incited to wage a war of genocide against the whites.

You can download the book "Voice of a Prophet" here:
https://archive.org/details/VanRensburg

https://www.youtube.com/watch?v=e-S1OnA3qAM

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https://www.youtube.com/watch?v=H81LWvZbhxQ

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The Horror... The Horror... The Horror...


The present invention relates to a microcapsulized coating material for killing arthropods, its preparation method and use. Said microcapsulized coating material comprises 0.25-2.0% of microcapsule aqueous suspension agent and 98-99.75% of water based coating material, in which the microcapsule aqueous suspension agent contains 0.1-5.0% of arthropod-killing effective component pyrethroid and fenitrothion, 0.08-0.94% of capsule wall material polymethyl polyphenyl isocyanate and hexamethylene-tetramine, 0.06-0.3% of dispersant agent, and the rest is water.

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https://www.naturalnews.com/2019-02-11-apple-demands-natural-news-stop-writing-about-abortions-or-satanism.html

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https://www.youtube.com/watch?v=wmKqAOM2sW0

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https://www.dailymail.co.uk/health/article-6704059/Diet-drinks-increase-risk-stroke-heart-disease.html

A major study of 80,000 women over 50 tracked their drinking over 12 years
Risk of heart disease was 29% higher and death by any cause 16% higher
Risks rose for obese or African-American women with no diabetes history
It adds to controversy around artificial sweeteners as a healthy sugar alternative

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https://clinicaltrials.gov/ct2/show/NCT00422357

Study Description
Brief Summary:
Diabetes mellitus is the most common metabolic disorder worldwide. Some herbs are traditionally used in treatment of type 2 diabetes mellitus (T2DM). Urtica Dioica (UD) or stinging nettle is traditionally used in Morocco, Turkey, Brasil, Jordan and with much frequency in northern Iran.

Studies on animal models along with in vitro studies has shown hypoglycemic effect for aqueous extract of UD.

This study aimed to investigate hypoglycemic effects of UD tea bags in patients with T2DM on glycemic control, insulin sensitivity, along with its effects on lipid profile (LP), blood pressure (BP), liver, and kidney function.

Detailed Description:
The study will be performed under randomized, double-blind, placebo controlled, and case-control design. The object of this study is patients with T2DM. Patients are randomly assigned to start with placebo tea bags (3 tea bags as 2-gram tea bag steamed in boiling water for 20 minutes: mixture of bran powder which is already boiled in water twice plus spinach powder) in control groups and UD tea bags (3 tea bags as 2-gram tea bag steamed in boiling water for 20 minutes) in patients with T2DM for two months. Every two weeks, fasting glucose, postprandial glucose after a standard breakfast, serum insulin, lipids, alanine amino transferase (ALT), aspartate amino transferase (AST), creatinine (to calculate GFR), along with blood pressure will be measured.

To the best of our knowledge, this is the first Randomized Clinical Trial.

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John Bolton has a sphincter under that toiletbrush:

https://fredoneverything.org/pussy-john-bolton-and-his-codpiece-mustache-examining-the-freak-show/

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Vaxxx yourself w/ MMR Enemas, Enemy @ Bill Gates ! --

https://jezebel.com/experts-say-those-who-dont-vaccinate-their-kids-tend-to-1832157679

https://abcnews.go.com/Health/parents-vaccinate-kids-tend-affluent-educated-experts/story?id=60674519

https://newspunch.com/educated-parents-vaccinate-children/

https://www.chicagomag.com/city-life/March-2014/Why-Is-Vaccine-Refusal-More-Prevalent-Among-the-Affluent/

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http://theeconomiccollapseblog.com/archives/35-mind-blowing-facts-about-america-that-previous-generations-of-americans-never-would-have-believed

 
The only thing that seems to be constant in our society is change, and today America is changing at a pace that is more rapid than we have ever seen before.  But is that a good thing or a bad thing?

For a moment, I would like for you to imagine what it would be like for a group of average Americans from 1919 to suddenly be transported to our time.  How do you think that they would feel about what we have become?  Certainly they would be absolutely amazed by our advanced technology, but beyond that they would almost certainly have very strong opinions about the current state of our society.  Similarly, if any of us were suddenly transported 100 years into the future, I am sure that we would be completely and utterly shocked by how things had changed.  The decisions that we make today are going to echo long into the future, and if we make very bad decisions there might not be a future for our country at all.

The following are 35 mind blowing facts about America that previous generations of Americans never would have believed…

    #1 Approximately one-fourth of the entire global prison population is in the United States.
    #2 By the time an American child reaches the age of 18, that child will have seen approximately 40,000 murders on television.
    #3 The average U.S. adult “logs 6 hours, 43 minutes of total screen time daily”.
    #4 Approximately 96 percent of all Americans use the Internet.
    #5 According to the American Road and Transportation Builders Association, nearly 56,000 bridges in the United States are currently “structurally deficient”.  What makes that number even more chilling is the fact that vehicles cross those bridges a total of 185 million times a day.
    #6 In more than half of all U.S. states, the highest paid public employee in the state is a football coach.
    #7 The Pentagon has more square footage of office space than any other office building in the entire world.
    #8 The state of Alaska is 429 times larger than the state of Rhode Island.  But Rhode Island has a significantly larger population than Alaska does.
    #9 Alaska has a longer coastline than all of the other 49 U.S. states put together.
    #10 The city of Juneau, Alaska is about 3,000 square miles in size. It is actually larger than the entire state of Delaware.
    #11 The average age of America’s dams is now 52 years.
    #12 The average supermarket in the United States wastes about 3,000 pounds of food each year.
    #13 There are more than 75 million dogs in the United States, and that number is constantly growing.
    #14 Montana has three times as many cows as it does people.
    #15 The grizzly bear is the official state animal of California. But no grizzly bears have been seen in the state since 1922.
    #16 The only place in the United States where coffee is grown commercially is in Hawaii.
    #17 More than 2 million Americans work for Wal-Mart.
    #18 Half of all American workers make less than $30,533 a year.
    #19 According to one recent survey, 37 percent of all Americans eat fast food every 24 hours.
    #20 One study found that one-third of all American teenagers haven’t read a single book in the past year.
    #21 Almost one-third of all Millennials are still living with their parents.
    #22 The suicide rate in the United States has risen by 33 percent since 1999.
    #23 Women have earned at least 57 percent of all bachelor’s degrees in the United States for 18 years in a row.
    #24 If the U.S. health care system was a country, it would have the fifth largest GDPon the entire planet.
    #25 America does not have a single airport that is considered to be in the top 25 in the world.
    #26 Today, a million Americans are living in their RVS, and that number is rising with each passing year.
    #27 More than 100 churches in the United States are dying every single week.
    #28 The original name of the city of Atlanta was “Terminus“.
    #29 There are three towns in the United States that have the name “Santa Claus“.
    #30 There is actually a town in Michigan called “Hell“, and during the recent polar vortex it actually froze over.
    #31 Almost one-third of all land in the United States is owned by the federal government.
    #32 More than 27 million acres of U.S. farmland is owned by foreigners.
    #33 Congestion on our highways costs Americans approximately 101 billion dollars a year in wasted fuel and time.
    #34 According to Bloomberg, it is being projected “that by 2025, shortfalls in infrastructure investment will subtract as much as $3.9 trillion from U.S. gross domestic product.”
    #35 In 1980, the U.S. national debt had just surpassed the one trillion dollar mark.  In 2019, we are about to surpass the 22 trillion dollar mark with no end in sight.

These days, just about everyone that tries to step forward and shake up the system is slapped with heavy criticism.

But at least they are trying to do something.

Holding an important position does not make you a leader.  Rather, being a leader is about having a positive vision for the future and doing whatever you can to achieve that vision.

We have way too many “leaders” out there that are simply filling seats.  Our country is literally falling apart at the seams, and all they can think about is protecting their careers.

America desperately needs change, but unfortunately we have very few change agents.  So we continue to steamroll toward our date with destiny, and time is not on our side.

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https://rense.com/

Mad Cow Disease In Deer (CWD) Spreading And Poses A Distinct Threat To Humans
US Gov Lies And Many Venison Eaters Will Die Of CWD Mad Deer Disease
Experts Worry CWD Mad Deer Disease Threatens $1 Billion MN Deer Hunting Industry
CWD Threatens The Public - Not Just Hunters
Mad Deer Disease Threatens AL Deer Pop
Man Eats Squirrel Brains, Now Dying From vCJD -- Squirrel Likely Had Mad Cow-CWD
CDC Denies 3 Men Who Ate Deer DiedFrom CWD Mad Deer Disease - Coverup
Mad Deer Disease Kills 30 Yr Old UT Hunter

https://www.livescience.com/63831-squirrel-brains-rare-disorder-creutzfeldt-jakob-disease.html

https://www.foodsafetynews.com/2019/02/fatal-brain-disease-in-deer-elk-moose-spreading-danger-for-humans/

http://www.cidrap.umn.edu/news-perspective/2003/02/cdc-finds-no-cwd-cjd-link-wisconsin-deaths

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https://www.zerohedge.com/news/2019-02-08/12000-chinese-blood-treatments-found-be-contaminated-hiv

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https://www.youtube.com/watch?v=yjNp7AuYNJE

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https://www.youtube.com/watch?v=m-g4Xt-VVzA

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https://www.sciencedaily.com/releases/2019/02/190204085956.htm

A new compound based on Iridium, a rare metal which landed in the Gulf of Mexico 66 M years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found.

The treatment of cancer using light, called Photodynamic therapy, is based on chemical compounds called photosensitizers, which can be switched on by light to produce oxidising species, able to kill cancer cells. Clinicians can activate these compounds selectively where the tumour is (using optical fibres) thus killing cancer cells and leaving healthy cells intact.

Thanks to the special chemical coating they used, the Warwick group was able to hook up Iridium to the blood protein Albumin, which then glowed very brightly so they could track its passage into cancer cells, where it converted the cells' own oxygen to a lethal form which killed them.

Not only is the newly formed molecule an excellent photosensitiser, but Albumin is able to deliver it into the nucleus inside cancer cells. The dormant compound can then be switched on by light irradiation and destroy the cancer cells from their very centre.

The bright luminescence of the iridium photosensitiser allowed its accumulation in the nucleus of tumour cells and its activation leading to the cancer cell death to be followed in real time using a microscope.

Professor Peter Sadler, from the Department of Chemistry at the University of Warwick comments:

"It is amazing that this large protein can penetrate into cancer cells and deliver iridium which can kill them selectively on activation with visible light. If this technology can be translated into the clinic, it might be effective against resistant cancers and reduce the side effects of chemotherapy"

Dr Cinzia Imberti, from the University of Warwick comments:

"It is fascinating how albumin can deliver our photosensitiser so specifically to the nucleus. We are at a very early stage, but we are looking forward to see where the preclinical development of this new compound can lead."

"Our team is not only extremely multidisciplinary, including biologists, chemists and pharmacists, but also highly international, including young researchers from China, India and Italy supported by Royal Society Newton and Sir Henry Wellcome Fellowships."

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201813002
https://doi.org/10.1002/anie.201813002
Abstract

An organoiridium–albumin bioconjugate (Ir1-HSA) was synthesized by reaction of a pendant maleimide ligand with human serum albumin. The phosphorescence of Ir1-HSA was enhanced significantly compared to parent complex Ir1. The long phosphorescence lifetime and high 1O2 quantum yield of Ir1-HSA are highly favorable properties for photodynamic therapy. Ir1-HSA mainly accumulated in the nucleus of living cancer cells and showed remarkable photocytotoxicity against a range of cancer cell lines and tumor spheroids (light IC50; 0.8–5 µm, photo-cytotoxicity index PI=40–60), while remaining non-toxic to normal cells and normal cell spheroids, even after photo-irradiation. This nucleus-targeting organoiridium-albumin is a strong candidate photosensitizer for anticancer photodynamic therapy.


The invention belongs to the technical field of medicine and particularly relates to a novel four-nuclear iridium complex as well as a preparation method and an application thereof. The four-nuclear iridium complex has very strong fluorescence, singlet oxygen is produced under light, and the four-nuclear iridium complex has higher fluorescence and singlet oxygen quantum yield than a mononuclear iridium complex. In a dark environment, the four-nuclear iridium complex has toxicity for tumor cells, but has very high cytotoxicity for tumor cells under light, so that the four-nuclear iridium complex can be applied to PDT (photodynamic therapy).

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https://www.sciencedaily.com/releases/2019/02/190206131956.htm


The United Nations estimates that more than 8 million tons of plastics flow into the oceans each year. A new chemical conversion process could transform the world's polyolefin waste, a form of plastic, into useful products, such as clean fuels and other items.

"Our strategy is to create a driving force for recycling by converting polyolefin waste into a wide range of valuable products, including polymers, naphtha (a mixture of hydrocarbons), or clean fuels," said Linda Wang, the Maxine Spencer Nichols Professor in the Davidson School of Chemical Engineering at Purdue University and leader of the research team developing this technology. "Our conversion technology has the potential to boost the profits of the recycling industry and shrink the world's plastic waste stock."

Wang, Kai Jin, a graduate student, and Wan-Ting (Grace) Chen, a postdoctoral researcher at Purdue, are the inventors of the technology, which can convert more than 90 percent of polyolefin waste into many different products, including pure polymers, naphtha, fuels, or monomers. The team is collaborating with Gozdem Kilaz, an assistant professor in the School of Engineering Technology, and her doctoral research assistant, Petr Vozka, in the Fuel Laboratory of Renewable Energy of the School of Engineering Technology, to optimize the conversion process to produce high-quality gasoline or diesel fuels.

The conversion process incorporates selective extraction and hydrothermal liquefaction. Once the plastic is converted into naphtha, it can be used as a feedstock for other chemicals or further separated into specialty solvents or other products. The clean fuels derived from the polyolefin waste generated each year can satisfy 4 percent of the annual demand for gasoline or diesel fuels. Some results of Wang's study were published Jan. 29 in ACS Sustainable Chemistry and Engineering.

Wang became inspired to create this technology after reading about the plastic waste pollution of the oceans, ground water, and the environment. Of all the plastics produced over the past 65 years (8.3 billion tons), about 12 percent have been incinerated and only 9 percent have been recycled. The remaining 79 percent have gone into landfills or the oceans. The World Economic Forum predicts that by 2050 the oceans will hold more plastic waste than fish if the waste continues to be dumped into bodies of water.

Wang said the technology could convert up to 90 percent of the polyolefin plastic.

"Plastic waste disposal, whether recycled or thrown away, does not mean the end of the story," Wang said. "These plastics degrade slowly and release toxic microplastics and chemicals into the land and the water. This is a catastrophe, because once these pollutants are in the oceans, they are impossible to retrieve completely."

The work aligns with Purdue's Giant Leaps celebration, acknowledging the global advancements in sustainability as part of Purdue's 150th anniversary. This is one of the four themes of the yearlong celebration's Ideas Festival, designed to showcase Purdue as an intellectual center solving real-world issues.

Wang said she hopes her technology will stimulate the recycling industry to reduce the rapidly rising amount of plastic waste. She and her team are looking for investors or partners to assist with demonstrating this technology at a commercial scale.

Wang's technology is patented through the Purdue Research Foundation's Office of Technology Commercialization.

Systems and methods for purifying or recycling polymeric materials such as polycarbonates are disclosed. Such methods may include performing two or more extractions using differing solvent media to remove non-target materials and attain a purified composition of a target polymer. Other steps including dissolution, precipitation, filtration, and/or centrifugation may also be performed in the methods of the present invention.

https://pubs.acs.org/doi/10.1021/acssuschemeng.8b03841
ACS Sustainable Chem. Eng., Article ASAP
DOI: 10.1021/acssuschemeng.8b03841
Wan Ting Chen , Kai Jin, and Nien-Hwa Linda Wang

In this study, model PP was converted into oil using supercritical water at 380–500 °C and 23 MPa over a reaction time of 0.5–6 h. Up to 91 wt % of model PP was converted into oil at 425 °C with a 2–4 h reaction time or at 450 °C with a 0.5–1 h reaction time. Higher reaction temperatures (>450 °C) or longer reaction times (>4 h) led to more gas products. The oil products consisted of olefins, paraffins, cyclics, and aromatics. About 80–90 wt % of the oil components had the same boiling point range as naphtha (25–200 °C) and heating values of 48–49 MJ/kg. Reaction pathways for converting model PP into oil under the tested conditions were proposed. Preliminary analyses indicate that this conversion process is net-energy positive and potentially has a higher energy efficiency and lower greenhouse gas emissions than incineration and mechanical recycling. The oil derived from PP has the potential to be used as gasoline blendstocks or feedstocks for other chemicals.

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https://www.eurekalert.org/pub_releases/2016-05/cp-ms051316.php
http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30518-6


Summary
Antibiotics, though remarkably useful, can also cause certain adverse effects. We detected that treatment of adult mice with antibiotics decreases hippocampal neurogenesis and memory retention. Reconstitution with normal gut flora (SPF) did not completely reverse the deficits in neurogenesis unless the mice also had access to a running wheel or received probiotics. In parallel to an increase in neurogenesis and memory retention, both SPF-reconstituted mice that ran and mice supplemented with probiotics exhibited higher numbers of Ly6Chi monocytes in the brain than antibiotic-treated mice. Elimination of Ly6Chi monocytes by antibody depletion or the use of knockout mice resulted in decreased neurogenesis, whereas adoptive transfer of Ly6Chi monocytes rescued neurogenesis after antibiotic treatment. We propose that the rescue of neurogenesis and behavior deficits in antibiotic-treated mice by exercise and probiotics is partially mediated by Ly6Chi monocytes.

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Thanks, DW (referral to rexresearch @ 19:00 re: Dr O.E. Wagner / W-Waves ):

https://www.youtube.com/watch?v=_NpqADtMhz4

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https://www.rt.com/news/450884-mice-bones-joints-regeneration-breakthrough/


Researchers have concluded a “transformational” study in which, for the first time, they have successfully regenerated joint as well as bone tissue in amputated mice, a step which holds great promise for human limb regeneration.

Scientists at Texas A&M University were able to artificially stimulate growth in damaged or amputated limbs of neonatal mice, using just two proteins: BMP2 and BMP9.

“These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,”explain the researchers in their paper.

Their new research indicates joint regrowth, a level of complexity hitherto unforeseen, which provides a critical step towards one day replacing human limbs. The scientists were attempting to recreate behavior typically displayed by reptilian cells in mammalian cells.

Cancer-fighting nanomeds can do more harm than good, new research says Cancer-fighting nanomeds can do more harm than good, new research says

“Our study is transformational,” Ken Muneoka from Texas A&M University, told New Scientist. “They can do it, they just don't do it,” he adds. “So, we have to figure out what's constraining them."

Bone regrowth has been achieved before, but without the additional protein, the bones would just heal over as normal rather than growing joint and cartilage tissue. Over 60 percent of the mice’s bone stumps formed a layer of cartilage within three days.

While admittedly just a small step, the research could ultimately provide breakthroughs in treatments for disorders like osteoarthritis as it would allow for replacement of cartilage from a person’s own cells rather than relying on transplants. 

“These findings provide further support for the view that cells of a non-regenerative mammalian amputation wound retain the positional information necessary to re-build structures removed by amputation,” the researchers concluded.

https://www.nature.com/articles/s41467-018-08278-4
Nature Communicationsvolume 10, Article number: 424 (2019)


Abstract
A major goal of regenerative medicine is to stimulate tissue regeneration after traumatic injury. We previously discovered that treating digit amputation wounds with BMP2 in neonatal mice stimulates endochondral ossification to regenerate the stump bone. Here we show that treating the amputation wound with BMP9 stimulates regeneration of a synovial joint that forms an articulation with the stump bone. Regenerated structures include a skeletal element lined with articular cartilage and a synovial cavity, and we demonstrate that this response requires the Prg4 gene. Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint. These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound...

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Run away already !!!

https://www.youtube.com/watch?v=Ycwe5oV0hHE

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https://www.youtube.com/watch?v=wOE4UegzJ_M

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https://www.youtube.com/watch?v=uGZrUASys6Q

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https://www.youtube.com/watch?v=bwDbwaV_mPQ

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"Christic" S&M = Love :

https://www.youtube.com/watch?v=V4nCaxHN-cY

https://www.sciencedaily.com/releases/2019/01/190130133209.htm

For decades, women have shouldered most of the burden of contraception. However, long-term use of female birth control pills could increase the risk for side effects such as blood clots or breast cancer. Now, inspired by colorful layered cocktails, researchers have developed a medium-term, reversible male contraceptive. They report their results in the journal ACS Nano.

Common forms of male contraception are either short-term (condoms) or long-term (vasectomy). However, condoms can fail, and vasectomies, while effective, are not often reversible. Xiaolei Wang and colleagues wanted to devise a medium-term, reversible form of male contraception. They drew inspiration from cocktails, such as the Galaxy, that bartenders make by layering colorful liquids in a glass. If the beverage is stirred or heated, the layers combine into a uniform liquid. Wang and colleagues wondered if they could use a similar approach to inject layers of materials to block the vas deferens, the duct that conveys sperm from the testicle to the urethra. Applying heat would cause the layers to mix, breaking them down and "unplugging the pipeline."

The team tested their approach in male rats. They sequentially injected four layers of materials into the vas deferens: a hydrogel that forms a physical barrier to sperm; gold nanoparticles, which heat up when irradiated with near-infrared light; ethylenediaminetetraacetic acid (EDTA), a chemical that breaks down the hydrogel and also kills sperm; and finally, another layer of gold nanoparticles. The injected materials kept the rats from impregnating females for more than 2 months. However, when the researchers shone a near-infrared lamp on the rats for a few minutes, the layers mixed and dissolved, allowing the animals to produce offspring. The researchers say that while this pilot experiment is promising, more research is needed to verify the safety of the materials.

ACS Nano, 2019; DOI: 10.1021/acsnano.8b06683

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Olga Malinkiewicz, et al.: Perovskite Film

https://www.afp.com/en/news/826/inkjet-solar-panels-poised-revolutionise-green-energy-doc-1cu3051


hat if one day all buildings could be equipped with windows and facades that satisfy the structure's every energy need, whether rain or shine?

That sustainability dream is today one step closer to becoming a reality thanks to Polish physicist and businesswoman Olga Malinkiewicz.

The 36-year-old has developed a novel inkjet processing method for perovskites -- a new generation of cheaper solar cells -- that makes it possible to produce solar panels under lower temperatures, thus sharply reducing costs.

Indeed, perovskite technology is on track to revolutionise access to solar power for all, given its surprising physical properties, some experts say.

"In our opinion, perovskite solar cells have the potential to address the world energy poverty," said Mohammad Khaja Nazeeruddin, a professor at Switzerland's Federal Institue of Technology Lausanne, an institution on the cutting-edge of solar energy research.

Solar panels coated with the mineral are light, flexible, efficient, inexpensive and come in varying hues and degrees of transparency.

They can easily be fixed to almost any surface -- be it laptop, car, drone, spacecraft or building -- to produce electricity, including in the shade or indoors.

Though the excitement is new, perovskite has been known to science since at least the 1830s, when it was first identified by German mineralogist Gustav Rose while prospecting in the Ural mountains and named after Russian mineralogist Lev Perovski.

In the following decades, synthesising the atomic structure of perovskite became easier.

But it was not until 2009 that Japanese researcher Tsutomu Miyasaka discovered that perovskites can be used to form photovoltaic solar cells.

- 'Bull's eye' -

Initially the process was complicated and required ultra high temperatures, so only materials that could withstand extreme heat -- like glass -- could be coated with perovskite cells.

This is where Malinkiewicz comes in.

In 2013, while still a PhD student at the University of Valencia in Spain, she figured out a way to coat flexible foil with perovskites using an evaporation method.

Later, she developed an inkjet printing procedure that lowered production costs enough to make mass production economically feasible.

"That was a bull's eye. Now high temperatures are no longer required to coat things with a photovoltaic layer," Malinkiewicz told AFP. They panels can easily be fixed to almost any surface

Her discovery quickly earned her an article in the journal Nature and media attention, as well as the Photonics21 Student Innovation award in a competition organised by the European Commission.

The Polish edition of the MIT Technology Review also selected her as one of its Innovators Under 35 in 2015.

She went on to cofound the company Saule Technologies -- named after the Baltic goddess of the sun -- along with two Polish businessmen.

They had to assemble all their laboratory equipment from scratch, before multimillionaire Japanese investor Hideo Sawada came on board.

The company now has an ultra-modern laboratory with an international team of young experts and is building an industrial-scale production site.

"This will be the world's first production line using this technology. Its capacity will reach 40,000 square metres of panels by the end of the year and 180,000 square metres the following year," Malinkiewicz said at her lab.

"But that's just a drop in the bucket in terms of demand."

Eventually, compact production lines could easily be installed everywhere, according to demand, to manufacture perovskite solar panels that are made to measure.

- Self-sufficient buildings -

The Swedish construction group Skanska is testing the cutting-edge panels on the facade of one of its buildings in Warsaw.

It also inked a licencing partnership with Saule in December for the exclusive right to incorporate the company's solar cell technology in its projects in Europe, the United States and Canada.

"Perovskite technology is bringing us closer to the goal of energy self-sufficient buildings," said Adam Targowski, sustainability manager at Skanska.

"Perovskites have proven successful even on surfaces that receive little sunlight. We can apply them pretty much everywhere," he told AFP.

"More or less transparent, the panels also respond to design requirements. Thanks to their flexibility and varying tints, there's no need to add any extra architectural elements."

A standard panel of around 1.3 square metres, at a projected cost of 50 euros ($57), would supply a day's worth of energy to an office workstation, according to current estimates.

Malinkiewicz insists that the initial cost of her products will be comparable to conventional solar panels.

Perovskite technology is also being tested on a hotel in Japan, near the city of Nagasaki.

Plans are also afoot for the pilot production of perovskite panels in Valais, Switzerland and in Germany under the wings of the Oxford Photovoltaics venture.

"The potential of the technology is clearly enormous," Assaad Razzouk, the CEO of Singapore-based Sindicatum Rewable Energy, a developer and operator of clean energy projects in Asia, told AFP.

"Just think of all the buildings one could retrofit worldwide!"


Optoelectronic film and method for producing optoelectronic film
PL420300

Inverted solar cell and process for producing the same
CN105900255

A FILM-FORMING COMPOSTION AND A METHOD FOR MANUFACTURNIG A PHOTOACTIVE FILM
EP3227394

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http://www.vrijewereld.org/pdf-bibliotheek/

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https://www.voltairenet.org/IMG/pdf/Sutton_Wall_Street_and_Hitler-4.pdf

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http://reciprocalsystem.org/PDFa/The%20Simple%20Essence%20of%20Dewey%20B.%20Larson%27s%20Reciprocal%20System%20of%20Physics%20(Boardman,%20Jameela).pdf

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https://www.youtube.com/watch?v=-Mxk3G6lqq4


Father Kosmas Aitolos was born in 1714 in the Greek village Megalo Dendro (Big Tree) in the region of Aitolia. He studied in Mount Athos, in “Athonias School”, and later he became a monk in Philotheou Monastery.  Because of the lack of education in most of the population, especially in the remote areas of Greece, Father Kosmas was “forced” to live Athos and begin missionary tours in the villages with the aim of educating the poor people. This way he would also be able to help people understand the Scriptures better. In a period of six years he managed to establish 250 schools as well as charities and rural churches.

On August 24, 1779 he was executed at Kolkondas, Fier District, near the mouth of the Seman river (in present day Albania) by the Ottoman authorities. There were no formal charges against him.

He was recognized as a saint by the Patriarchate of Constantinople Athenagoras in 1961.

St. Kosmas received from God the gift of prophecy. He seems to have foreseen everything. He predicted the future of the world, he warned of the great cataclysms which await us in our Apocalyptic times but also he foretold the new technological developments.

Some of them became reality and others are about to be fulfilled.

In the following quotes several of his prophecies are presented.

PROPHECIES AND SAYINGS

You will see people flying in the sky like blackbirds and hurling fire on the earth. Those alive then will run to the graves and shout: “Come out, you who are dead, and let us who are living in.”

The cause of the general war will come from Dalmatia. Austria will be dismembered first and then Turkey.

That which is desired [i.e., freedom] will come in the third generation. Your grandchildren will see it.

France will liberate Greece, [while] Italy (will liberate) Epiros.

The villages of the plain will suffer destruction, while people at the foot of (Mount) Kissavo will go to sleep slaves and will awaken free.

The time will come when your enemies will take away from you even the ashes from your fires, but don’t give up your faith as others will do.

The red hats [ie., the French] will come here [Kephallenia], and then the English for fifty-four years, and then this place will become Roman [i.e., Greek Orthodox].

The time will come when people will speak from one far place to another, for example, from Constantinople to Russia, as though they were in adjoining rooms.

A time will come when the harmony that exists now be­tween clergy and laymen will not be.

The time will come when the devil will make his turns with his pumpkin.

They will put a tax on chickens and on windows.

Clergymen will become worse and more impious than everyone.

There will come a time when your enemies will even take away from you the ashes from your fire, but do not deny your faith, as others may do.

People will become impoverished because they will have no love for trees.

You will see in the plain a carriage without horses which will run faster than a rabbit.

The rich will become poor and the poor will die.

The time will come when the Romans [i.e., the Greek Orthodox] will fight among themselves. I recommend harmony and love.

A foreign army will come. It will believe in Christ, but it will not speak the (Greek) language.

After the general war, the wolf will live with the lamb.

People will become poor because they will become lazy.

They will seek to take you as soldiers, but they will not do so in time.

The Turks will learn the secret three days sooner than the Christians.

When you hear that the war has started from below (the south), then it will be near.

If the war starts from below (the south), you will suffer little. If it starts from above (the north), you will be destroyed.

The crags and the pits will be full of people.

It will come quickly. And either the ox will be in the field or the horse on the threshing floor.

It is sad for me to say it to you: today, tomorrow we will endure thirst and great hunger such that we would give thousands of gold coins but still will not find a little bread.

After the war, a man will have to run half an hour to find another human being to join him in fellowship.

They will ask for your rifles. Retain two. Give one and keep the other. A single rifle will save a hundred souls.

Out of schools will come things which your mind can’t imagine.

Have a cross on your forehead so that they know that you are Christian.

There will come a time when your enemies will even take away from you the ashes from your fire, but do not deny your faith, as others may do.

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http://www.guaduabamboo.com/making-bamboo-cables.html
http://greaterancestors.com/bamboo-cable-steel/


Marco Polo  described how the Chinese used and manufactured bamboo cables for towing boats.

Engineers experimenting for the Whangpoo Conservancy Board found out that these twisted and plaited bamboo cables were made with material taken from the outer layer of the bamboo (which was only 1/8 inch or 3 mm thick). They estimated that the working stress was about 20,000 pounds per square inch, which was of the same order as normally taken by steel wires of the same size.

The breakages were very few with bamboo cables. Moreover, while hempen ropes lose some 25 percent of their strength when wet, the tensile strength of plaited bamboo cables increases about 20 percent when they are fully saturated with water. Bamboo cables were available in lengths up to a quarter mile.

Bamboo cables were the earliest structural element in the history of engineering to be used for suspension bridges, which originated in western China and the Himalayas.

Primitive bridges made of bamboo cables droop across gorges with one end fixed lower than the other. Bamboo tubes greased with yak butter slide down the cables, with a cradle hanging from them in which people and animals side. Of great strength, a bamboo cable of 2 inch diameter could support 4 ton, these ancient bridges spanned distances up to 76 meters without central supports.

Later on, various designs combined whole bamboo culms, woven slats, and cables braided of workable species such as Gigantochloa apus, which was a favorite for bridges in Java.

The Anlan Bridge

The remarkable Anlan bridge on the Min River in China was first constructed around 300 AD. Historians consider this bridge one of the engineering marvels of the ancient world.

Bamboo cables have a tensile strength of up to 26,000 pounds per square inch, while hemp rope can only carry a stress of 8,000 pounds.

The Anlan suspension bridge spans the 1,000-foot wide Min River, is 9 feet wide, and was built entirely of bamboo cables resting on seven supports fixed equidistant in the bed of the stream. The floor of the bridge rested across 10 bamboo cables, each 21 inches in circumference, and five similar cables on each side form the rails.

Moreover, the silica-containing outer surface is very resistant to wear, e.g., against rock surfaces, which is naturally important both in towing and bridge cables.

Some Related Patents:

METHOD FOR MANUFACTURING COMPRESSED AND HARDENED BODY OF BAMBOO FIBRES, AND COMPRESSED AND HARDENED BODY OF BAMBOO FIBRES MANUFACTURED BY SAID METHOD
WO2017204360

Bamboo fiber production technology
CN105734743

GB296333
Processes for the treatment of plant materials in the preparation of fibres
 
CN106584629
Manufacture process for recombined bamboo

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https://www.capitolhilloutsider.com/islams-conquest-of-america-through-creeping-sharia/

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Keith Clark : I recorded one full year of tones. It is all documented, here is a sample of me being sent tones....it turned out to be music.... My work is centered around life after death.... with a specialty in radio. I
use live noise reduction/filtering and stream it back to the internet live. Over 13 years I've recorded many amazing things (in static), actually it's
a joint effort between myself and whomever the communicators are. I try to build up energy and speak to them... To keep it short, I believe I have received both tones and guttural voices.
 
https://www.youtube.com/playlist?list=PLLB-82YMhiPEC2lKS8kGFvmy_1Kowazj3

https://idigitalmedium.com/

A NONPROFIT ORGANIZATION FOR RESEARCH, EDUCATION, AND PRESERVATION OF DATA REGARDING LIFE AFTER DEATH AND BEYOND
Instrumental Transcommunication

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http://www.worldwatch.org/node/4803

Scientists have created a solar cell device that is significantly more efficient than conventional photovoltaic cells.

For the first time, scientists have produced a photovoltaic (PV) cell with a conversion efficiency of 40.7 percent, the U.S. Department of Energy (DOE) reported on December 7. The collaboration of DOE and Spectrolab, Inc. (a subsidiary of Boeing) led to the achievement of a decades-long goal: to break the 40-percent efficiency barrier on solar cell devices. “We are eager to see this accomplishment translate into the marketplace as soon as possible,” Alexander Karsner, assistant secretary for energy efficiency and renewable energy at DOE, said.

The breakthrough cell was developed using a structure called a “multi-junction solar cell.” In this type of device, individual PV cells are made of layers, and each layer captures a portion of the sunlight reaching the cell. This allows the unit to capture energy from a greater range of the solar spectrum, leading to higher efficiency. According to Dr. Richard King, a principal investigator at Spectrolab, “The excellent performance of these materials hints at still higher efficiency in future solar cells.”

According to Spectrolab, the highly efficient units allow for the use of fewer cells overall to achieve the same power output as conventional silicon cells. As a result, the technology may allow for lower PV system installation costs, at $3 per watt, and electricity production costs of $0.08–$0.10 cents per kilowatt-hour. The acheivement has the greater potential of helping to reduce the U.S. reliance on imported oil and increase national energy security, DOE’s Karsner notes.

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https://www.theepochtimes.com/huge-barrier-isnt-trapping-plastic-waste-in-pacific-ocean_2742281.html


LOS ANGELES—A floating device sent to corral a swirling island of trash between California and Hawaii has not swept up any plastic waste—but the young innovator behind the project said on Dec. 17, that a fix was in the works.

Boyan Slat, 24, who launched the Pacific Ocean cleanup project, said the speed of the solar-powered barrier isn’t allowing it to hold on to the plastic it catches.

“Sometimes the system actually moves slightly slower than the plastic, which of course you don’t want because then you have a chance of losing t

he plastic again,” Slat said in an interview with The Associated Press.

A crew of engineers will reach the U-shaped boom on Dec. 18, and will work for the next few weeks to widen its span so that it catches more wind and waves to help it go faster, he said.

A ship towed the 2,000-foot barrier in September from San Francisco to the Great Pacific Garbage Patch—an island of trash twice the size of Texas. It has been in place since the end of October, Slat said.

The plastic barrier with a tapered 10-foot-deep screen is intended to act like a coastline, trapping some of the 1.8 trillion pieces of plastic that scientists estimate are swirling in the patch while allowing marine life to safely swim beneath it.

So far the giant floating device, launched three months ago to collect plastic in the Pacific garbage patch has not been successful. But the Ocean Cleanup’s founder said, with changes, he’s confident it’ll still work.

Slat said he is not deterred by the setback because engineers expected to make tweaks to the system...

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https://www.theepochtimes.com/study-finds-clear-evidence-linking-cellphone-radiation-to-tumors-in-rats_2709524.html

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https://www.youtube.com/watch?v=GD30QvUJfXQ

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http://avalonlibrary.net/ebooks/Joseph%20P.%20Farrell%20-%20Covert%20Wars%20and%20Breakaway%20Civilizations%20-%20The%20Secret%20Space%20Program,%20Celestial%20Psyops%20and%20Hidden%20Conflicts.pdf

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http://www.mediafire.com/file/xfshct650g6b7wu/367844333333.pdf

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http://concerneduspatriots.com/fema-director-calls-citizens-cattle/

During a government shutdown that furloughed hundreds of thousands of workers, the Federal Emergency Management Agency (FEMA) continued operating and quietly received a $400,000,000 budget increase to further its insidious agenda to enslave or eradicate a majority of the population. At an agency meeting last Tuesday, FEMA Director Brock Long told regional subordinates that citizens who question the agency’s mission are “nothing more than cattle” and must be treated as hostile combatants.

He cited a recent disturbance in fire-stricken Paradise, CA; local subversives, he said, protested FEMA’s presence by forming a human blockade to prevent agents from unlawfully trespassing on private property or entering the charred remains of scorched homes and businesses. A group of approximately twenty-five persons held protest signs reading “FEMA, WE DON’T WANT YOU HERE” and “FEMA, GO HOME.”

Long told colleagues that agents must not hesitate to use discreet, lethal force if citizens defy FEMA’s authority, and reminded them that powers granted by the Patriot Act absolve agents of criminal maleficence when acting in the line of duty.  He warned them, however, not to shoot anybody in the presence of media personalities.

Our FEMA source said the following: “Brock Long continues to perceive everyday people as a threat to his authority. And what happened in California has strengthened his paranoia. He wants the population subservient to FEMA. To him, you’re all livestock ready for the slaughterhouse. We’re talking about a man who has ordered agents to toss people off boats.  Even supervisors who disagree with his policies are powerless to stop him.”..

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jsr.12597
https://doi.org/10.1111/jsr.12597

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https://science.news/2018-12-04-south-african-plant-displays-impressive-anti-diabetic-profile.html


A South African study, which was published in the journal Pharmacognosy Research, discovered that the bushy bulbine (Bulbine abyssinica) is rich in polyphenols that contribute to its antidiabetic and antioxidant activities. This finding was based on the results of different in vitro studies....

http://www.phcogres.com/article.asp?issn=0974-8490;year=2018;volume=10;issue=1;spage=72;epage=80;aulast=Odeyemi
DOI: 10.4103/pr.pr_55_17
Abstract        
Background: Bulbine abyssinica has been reported to possess a variety of pharmacological activities traditionally. Previous work suggested its antidiabetic properties, but information on the antidiabetic compounds is still lacking. Objective: The present research exertion was aimed to isolate and identify biologically active polyphenols from B. abyssinica leaves and to evaluate their efficacy on carbohydrate digesting enzymes. Materials and Methods: Fractionation of the polyphenolic contents from the methanolic extract of B. abyssinica leaves was executed by the silica gel column chromatography to yield different fractions. The antioxidant activities of these fractions were carried out against 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS), 2,2-diphenyl-1-picrylhydrazyl radicals, and ferric ion-reducing antioxidant power (FRAP). In vitro antidiabetic experimentation was performed by evaluating the a-amylase and a-glucosidase inhibitory capacity. The isolated polyphenols were then identified using liquid chromatography and mass spectroscopy (LC/MS). Results: Out of the eight polyphenolic fractions (BAL 1–8), BAL-4 has the highest inhibitory activity against ABTS radicals whereas BAL-6 showed potent ferric ion-reducing capacity. BAL-5 was the most effective fraction with antidiabetic activity with IC50of 140.0 and 68.58 ± 3.2 µg/ml for a-amylase and a-glucosidase inhibitory activities, respectively. All the fractions competitively inhibited a-amylase, BAL-5 and BAL-6 also inhibited a-glucosidase competitively, while BAL-4 and BAL-1 exhibited noncompetitive and near competitive inhibitions against a-glucosidase, respectively. The LC/MS analysis revealed the presence of carvone in all the fractions. Conclusions: The present study demonstrates the antioxidant and antidiabetic activities of the isolated polyphenols from B. abyssinica.

Summary
Polyphenols were successfully isolated and identified from Bulbine abyssinica leaves
The isolated polyphenols are biologically active with high antioxidant as well as inhibitor of carbohydrate-digesting enzymes
B. abyssinica can be a good source of amylase and glucosidase inhibitors
B. abyssinica can be used as complementary or alternative therapeutic agents especially for the treatment of diabetes
Carvone, quercetin, and psoralen could be the compounds responsible for the a-amylase and a-glucosidase inhibitory activities.

Introduction
Plants produce a variety of secondary products having one or more hydroxyl functional groups on an aromatic ring called phenol.[1] These plant phenolics play important role in the plant defense mechanism against diseases and pests.[2] Phenolic acids can be classified into derivatives of benzoic acid and caffeic acid. Example of the benzoic derivative is the gallic acid while examples of the caffeic acid are coumaric and ferulic acids.[3] However, flavonoids, flavonols, tannins, lignins, and stilbenes are examples of plant phenolics. Plant phenolics have been used as food additives due to their distinctive odor and as ingredients in perfume. Recently, much attention has been focused on the potent antioxidative properties of polyphenolics and conversely their effects in the prevention of various oxidative stress-associated diseases. Free radicals are produced during oxidation processes and have been implicated in the cause of many human diseases such as cancer, diabetes, atherosclerosis, inflammation, cardiac, Alzheimer's, kidney, liver diseases, and aging.[3],[4],[5] The prevention of oxidative stress by plant polyphenols and their use in treatment of diseases is of increasing importance from the epidemiological data as well as in vitro and in vivo studies.[6] Asteraceae have been reported to be the largest family of flowering plants with many of its members shown to have pharmacological activities which contained important phytochemicals including polyphenolics and diterpenoids.[7],[8]Bulbine abyssinica A. rich belongs to this family and has been previously described to be rich in polyphenolics.[9] Further studies on the acetone and water extracts from the whole plant evaluated in vitro assays showed antioxidant potential, hypoglycemic, and advanced glycation end-products inhibition capacity.[9] In this study, antioxidant and antidiabetic properties of different polyphenol fractions were investigated through bioassay-guided isolation from the leaves of B. abyssinica...

Preparation of plant extracts and fractionation
The dried B. abyssinica leaves were washed, dried, and finely chopped using a grinder and then about 1 kg was macerated with methanol for 5 days and the extract evaporated under reduced pressure at 40°C, affording 200 g of the crude extract. This was then loaded into a glass column containing silica gel 60 (0.063–0.200 nm) that has been previously washed with methanol and then eluted with methanol/ethyl acetate (2:8), ethyl acetate/hexane (7:3), methanol/ethyl acetate (8:2), and methanol to yield 8 fractions (BAL-1 to BAL-8). The elutions were examined by thin-layer chromatography and each one of them was dried, weighed, and reconstituted with methanol to prepare a stock solution at concentration of 1 mg/ml for preliminary screening of total phenolic contents, flavonoids, proanthocyanidins, 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), and DPPH scavenging activity. The fractions having the best polyphenolic contents and antioxidant activity were selected for further experiments; these fractions are BAL-4, BAL-6, BAL-5, BAL-8, BAL-7, and BAL-1 in the order of their activity...

Conclusions
Based on the results of this study, it can be concluded that the polyphenolics isolated from B. abyssinica have significant antioxidant activities and inhibitory properties against a-amylase and a-glucosidase enzymes. The antidiabetic activities could be as a result of the carvone, quercetin, and psoralen contents of the plant. Therefore, B. abyssinica is an easily accessible source of natural antioxidants and antidiabetic compounds. This also confirms the folkloric usage of the plant for the treatment of diabetes. However, further studies need to be carried out on the isolation, purification, and elucidation of the structural properties of these compounds.

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https://www.sciencedaily.com/releases/2018/12/181231103951.htm


Helping the immune system clear away old cells in aging mice helped restore youthful characteristics

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future. The results of this research, led by Prof. Valery Krizhanovsky and Dr. Yossi Ovadya in the Molecular Cell Biology Department, were recently published in Nature Communications.

The research began with an investigation into the way that the immune system is involved in a crucial activity: clearing away old, senescent cells that spell trouble for the body when they hang around. Senescent cells -- not completely dead but suffering loss of function or irreparable damage -- have been implicated in diseases of aging by promoting inflammation. The researchers used mice in which a crucial gene for this immune activity was missing. At two years (elderly, for mice), the bodies of these mice had a greater accumulation of senescent cells compared with the mice in which the gene for removing these cells was intact. The mice missing the gene suffered from chronic inflammation, and various functions in their bodies appeared to be diminished. They also looked older -- and died earlier -- than their normal counterparts.

Next, the researchers gave the mice a drug that inhibits the function of certain proteins that help the aging cells survive in their senescent state, to see if this would contribute to the removal of these cells from the body. The drugs were administered to mice whose aging was a result of the malfunctions the group had uncovered in the immune system as well as those suffering premature aging from a different genetic error. The treated mice responded exceptionally well to the drug: Their blood tests and activity tests showed improvement, and their tissues appeared to be much closer to those of young mice. The scientists counted senescent cells, finding many fewer of them remaining in the treated mice's bodies; and when they looked for signs of inflammation, they found that this, too, was significantly lower. The mice treated with the drug were more active and their median lifespan rose....

The scientists intend to continue exploring ways to prompt the human body to remove its old senescent cells, particularly to find means of activating the immune system to do this job. That is, if future experimentation proves their theories correct, they could end up creating truly "anti-aging" therapies.

Nature Communications, 2018; 9 (1)
DOI: 10.1038/s41467-018-07825-3

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https://b-ok.cc/book/498613/369b78

Premised on the idea that one cannot know a science without knowing its history, History of Wireless offers a lively new treatment that introduces previously unacknowledged pioneers and developments, setting a new standard for understanding the evolution of this important technology.Starting with the background-magnetism, electricity, light, and Maxwell's Electromagnetic Theory-this book offers new insights into the initial theory and experimental exploration of wireless. In addition to the well-known contributions of Maxwell, Hertz, and Marconi, it examines work done by Heaviside, Tesla, and passionate amateurs such as the Kentucky melon farmer Nathan Stubblefield and the unsung hero Antonio Meucci. Looking at the story from mathematical, physics, technical, and other perspectives, the clearly written text describes the development of wireless within a vivid scientific milieu. 

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https://b-ok.cc/book/489790/eea343

Now in its second edition, this bestselling textbook may be the single most influential study of the historical relationship between science and technology ever published. Tracing this relationship from the dawn of civilization through the twentieth century, James E. McClellan III and Harold Dorn argue that technology as "applied science" emerged relatively recently, as industry and governments began funding scientific research that would lead directly to new or improved technologies. McClellan and Dorn identify two great scientific traditions: the useful sciences, patronized by the state from the dawn of civilization, and scientific theorizing, initiated by the ancient Greeks. They find that scientific traditions took root in China, India, and Central and South America, as well as in a series of Near Eastern empires, during late antiquity and the Middle Ages. From this comparative perspective, the authors explore the emergence of Europe and the United States as a scientific and technological power.The new edition reorganizes its treatment of Greek science and significantly expands its coverage of industrial civilization and contemporary science and technology with new and revised chapters devoted to applied science, the sociology and economics of science, globalization, and the technological systems that underpin everyday life. 

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https://b-ok.cc/book/550995/c31ec1

Today technology has created a world of dazzling progress, growing disparities of wealth and poverty, and looming threats to the environment. Technology: A World History offers an illuminating backdrop to our present moment--a brilliant history of invention around the globe. Historian Daniel R. Headrick ranges from the Stone Age and the beginnings of agriculture to the Industrial Revolution and the electronic revolution of the recent past. In tracing the growing power of humans over nature through increasingly powerful innovations, he compares the evolution of technology in different parts of the world, providing a much broader account than is found in other histories of technology. We also discover how small changes sometimes have dramatic results--how, for instance, the stirrup revolutionized war and gave the Mongols a deadly advantage over the Chinese. And how the nailed horseshoe was a pivotal breakthrough for western farmers. Enlivened with many illustrations, Technology offers a fascinating look at the spread of inventions around the world, both as boons for humanity and as weapons of destruction.

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https://b-ok.cc/book/553897/acc8d1

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https://www.americanthinker.com/articles/2018/01/what_i_learned_in_peace_corps_in_africa_trump_is_right.html


Three weeks after college, I flew to Senegal, West Africa, to run a community center in a rural town.  Life was placid, with no danger, except to your health.  That danger was considerable, because it was, in the words of the Peace Corps doctor, "a fecalized environment."

In plain English: s--- is everywhere.  People defecate on the open ground, and the feces is blown with the dust – onto you, your clothes, your food, the water.  He warned us the first day of training: do not even touch water.  Human feces carries parasites that bore through your skin and cause organ failure.

Never in my wildest dreams would I have imagined that a few decades later, liberals would be pushing the lie that Western civilization is no better than a third-world country.  Or would teach two generations of our kids that loving your own culture and wanting to preserve it are racism.

Last time I was in Paris, I saw a beautiful African woman in a grand boubou have her child defecate on the sidewalk next to Notre Dame Cathedral.  The French police officer, ten steps from her, turned his head not to see.

I have seen.  I am not turning my head and pretending unpleasant things are not true.

Senegal was not a hellhole.  Very poor people can lead happy, meaningful lives in their own cultures' terms.  But they are not our terms.  The excrement is the least of it.  Our basic ideas of human relations, right and wrong, are incompatible.

As a twenty-one-year-old starting out in the Peace Corps, I loved Senegal.  In fact, I was euphoric.  I quickly made friends and had an adopted family.  I relished the feeling of the brotherhood of man.  People were open, willing to share their lives and, after they knew you, their innermost thoughts.

The longer I lived there, the more I understood: it became blindingly obvious that the Senegalese are not the same as us.  The truths we hold to be self-evident are not evident to the Senegalese.  How could they be?  Their reality is totally different.  You can't understand anything in Senegal using American terms.

Take something as basic as family.  Family was a few hundred people, extending out to second and third cousins.  All the men in one generation were called "father."  Senegalese are Muslim, with up to four wives.  Girls had their clitorises cut off at puberty.  (I witnessed this, at what I thought was going to be a nice coming-of-age ceremony, like a bat mitzvah or confirmation.)  Sex, I was told, did not include kissing.  Love and friendship in marriage were Western ideas.  Fidelity was not a thing.  Married women would have sex for a few cents to have cash for the market.

What I did witness every day was that women were worked half to death.  Wives raised the food and fed their own children, did the heavy labor of walking miles to gather wood for the fire, drew water from the well or public faucet, pounded grain with heavy hand-held pestles, lived in their own huts, and had conjugal visits from their husbands on a rotating basis with their co-wives.  Their husbands lazed in the shade of the trees.

Yet family was crucial to people there in a way Americans cannot comprehend.

The Ten Commandments were not disobeyed – they were unknown.  The value system was the exact opposite.  You were supposed to steal everything you can to give to your own relatives.  There are some Westernized Africans who try to rebel against the system.  They fail.

We hear a lot about the kleptocratic elites of Africa.  The kleptocracy extends through the whole society.  My town had a medical clinic donated by international agencies.  The medicine was stolen by the medical workers and sold to the local store.  If you were sick and didn't have money, drop dead.  That was normal.

So here in the States, when we discovered that my 98-year-old father's Muslim health aide from Nigeria had stolen his clothes and wasn't bathing him, I wasn't surprised.  It was familiar.

Go to the post office, and the clerk would name an outrageous price for a stamp.  After paying the bribe, you still didn't know it if it would be mailed or thrown out.  That was normal.

One of my most vivid memories was from the clinic.  One day, as the wait grew hotter in the 110-degree heat, an old woman two feet from the medical aides – who were chatting in the shade of a mango tree instead of working – collapsed to the ground.  They turned their heads so as not to see her and kept talking.  She lay there in the dirt.  Callousness to the sick was normal.

Americans think it is a universal human instinct to do unto others as you would have them do unto you.  It's not.  It seems natural to us because we live in a Bible-based Judeo-Christian culture.

We think the Protestant work ethic is universal.  It's not.  My town was full of young men doing nothing.  They were waiting for a government job.  There was no private enterprise.  Private business was not illegal, just impossible, given the nightmare of a third-world bureaucratic kleptocracy.  It is also incompatible with Senegalese insistence on taking care of relatives.

All the little stores in Senegal were owned by Mauritanians.  If a Senegalese wanted to run a little store, he'd go to another country.  The reason?  Your friends and relatives would ask you for stuff for free, and you would have to say yes.  End of your business.  You are not allowed to be a selfish individual and say no to relatives.  The result: Everyone has nothing.

The more I worked there and visited government officials doing absolutely nothing, the more I realized that no one in Senegal had the idea that a job means work.  A job is something given to you by a relative.  It provides the place where you steal everything to give back to your family.

I couldn't wait to get home.  So why would I want to bring Africa here?  Non-Westerners do not magically become American by arriving on our shores with a visa.

For the rest of my life, I enjoyed the greatest gift of the Peace Corps: I love and treasure America more than ever.  I take seriously my responsibility to defend our culture and our country and pass on the American heritage to the next generation.

African problems are made worse by our aid efforts.  Senegal is full of smart, capable people.  They will eventually solve their own country's problems.  They will do it on their terms, not ours.  The solution is not to bring Africans here.

We are lectured by Democrats that we must privilege third-world immigration by the hundred million with chain migration.  They tell us we must end America as a white, Western, Judeo-Christian, capitalist nation – to prove we are not racist.  I don't need to prove a thing.  Leftists want open borders because they resent whites, resent Western achievements, and hate America.  They want to destroy America as we know it.

As President Trump asked, why would we do that?

We have the right to choose what kind of country to live in.  I was happy to donate a year of my life as a young woman to help the poor Senegalese.  I am not willing to donate my country.

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Dated 2012, but these products are pre-piss corpcash that should be girlcotted :

https://www.ashtarcommandcrew.net/forum/topics/comprehensive-list-of-companies-that-use-aborted-fetal-cells-as
http://www.cogforlife.org/fetalproductsall.pdf
https://cogforlife.org/wp-content/uploads/fetalproductsall.pdf

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Giving new definition to "hottie" -- Stupit sadomasochist Muslim idiots punk-rule over craven / suicidal EuroUnion dupes --

https://voiceofeurope.com/2019/01/african-child-abuse-tradition-of-breast-ironing-on-the-rise-in-uk/

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https://www.youtube.com/watch?time_continue=60&v=j4GpGHgOHAk

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https://list25.com/25-strongest-materials-known-to-man/
https://www.youtube.com/watch?v=0i4tNUx1a1M

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https://www.youtube.com/watch?v=DjCIye1UvP8

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You tell 'em, Mike !

https://www.naturalnews.com/2019-01-27-to-save-america-trump-must-declare-a-new-american-revolution.html
Sunday, January 27, 2019

It is becoming increasingly obvious to nearly everyone that the anti-Trump deep state is utterly out of control. A rogue, lawless cabal of treasonous criminals is now horrifyingly close to overthrowing democracy and achieving the permanent installation of a corrupt authoritarian regime that will rule over America like the KGB...

https://www.brighteon.com/5994020421001

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You tell 'em, Mark !

https://www.youtube.com/watch?v=xVvVEhdf7vw&feature=youtu.be
"Government is Slavery."

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